Sorry, but no. Minnie Driver isn't in Playing By Heart.

wait, sorry, revised guess after being confused:
Connection one: Return to me has a character who is nervous about meeting a guy because of her heart surgery, so there's a heart-heart connection.

Connection two: David Duchovney (X-Files, Playing God) is in Return to Me, Gillian Anderson (X-Files) is in Playing by Heart

No, it's not "New Hotness" (aka Miranda Otto, for those not in the loop), it's actually country-singer Sara Evans. (The icon I'm using for this is also Sara.) She's pretty and I love her songs. She's one of three country people I will actually listen to on a regular basis.